Protecting the heart from chemotherapy
About the project:
Using heart muscle cells produced from stem cells in the laboratory we are looking for drugs that stop the damage that occurs during chemotherapy. We are testing how these drugs function to protect heart muscle cells using miniature human hearts called organoids.
Importantly, we are using approved drugs enabling us to quickly move toward the clinic for trials designed to establish if these compounds work in patients to protect the hearts of children undergoing chemotherapy.
Research theme: reSOLVE
Tissue of interest: Heart